Gene-edited crops should be subject to the same stringent regulations as conventional genetically modified (GM) organisms, Europe’s highest court ruled on 25 July. The decision, handed down by the Court of Justice of the European Union (ECJ) in Luxembourg, is a major setback for proponents of gene-edited crops, including scientists. They had hoped that organisms created usingprecise gene-editing technologies such as CRISPR–Cas9 would be exempted from existing European law that has limited the planting and sale of GM crops. Instead, the ECJ ruled that crops created using these technologies are subject to a 2001 directive. That law was developed for older breeding techniques, and it imposes high hurdles for developing GM crops for food.